• 姓       名:黄昊文
  • 职       称:教授
  • 学       位:博士
  • 所在机构:湖南科技大学 化学化工学院
  • 出生年月: 1969年02月
  • 籍       贯:
  • 研究方向:纳米材料制备与性质;纳米化学/生物传感器的构建与应用;高灵敏度可视化检测方法
个人简介 学术成果 发表论文

教育背景

毕业于中国科学院化学研究所。

工作经历

美国德克萨斯大学圣安东尼奥分校访问学者(2016.3-2017.3), 2009、2011年两度赴香港城市大学进行合作研究。

先后主持三项国家自然科学基金(目前在研两项),已完成国家自然科学基金、湖南省自然科学基金、湖南省教育厅青年项目、国家重点实验室开放课题等多项研究项目。

以第一作者或通讯联系人身份在《Biomaterials》、《Analytical Chemistry》、《Chemical Communications》、《Biosensor and Bioelectronics》、《ACS Applied Materials and Interfaces》等国际刊物上发表科研论文40余篇。

已授权国家发明专利11项。

科研项目

[1]基于碳点及复合物模拟酶构建食品中金黄色葡萄球菌及肠毒素的现场、快速检测方法研究(项目编号:21675049),2017.01-2020.12.

[2]可控纳米结构表面等离子体共振生物传感器的构建及肝癌早期检测研究(项目编号:21375036),2014.01-2017.12.

[3]核壳型纳米棒构建生物传感器阵列的研究(项目编号:21075035),2011.01-2013.12.

论文专著

1.Haowen Huang*, Lanfang Liu, Lingyang Zhang, Qian Zhao, Yuan Zhou, Shishan Yuan, Zilong Tang, Xuanyong Liu. Peroxidase-Like Activity of Ethylene Diamine Tetraacetic Acid and Its Application for Ultrasensitive Detection of Tumor Biomarkers and Circular Tumor Cells, Analytical Chemistry, 2017, 89, 666–672.

2.Haowen Huang*, Yuan Zhou, Qian Zhao, Lingyang Zhang, Lanfang Liu, Xiaodong Xia, Shoujun Yi, A highly sensitive EDTA-based senor for detection of disease biomarker and drug, Sensors and Actuators B, 2017, 249, 478-485.

3.Qian Zhao, Haowen Huang*, Lingyang Zhang, Linqian Wang, Yunlong Zeng, Xiaodong Xia, Fengping Liu, Yi Chen*, Strategy To Fabricate Naked-Eye Readout Ultrasensitive Plasmonic Nanosensor Based on Enzyme Mimetic Gold Nanoclusters, Analytical Chemistry, 2016, 88, 1412–1418.

4.Lingyang Zhang, Donghui Wang, Haowen Huang*, Lanfang Liu, Yuan Zhou, Xiaodong Xia, Keqin Deng, Xuanyong Liu*,Preparation of Gold–Carbon Dots and Ratiometric Fluorescence Cellular Imaging,ACS Appl. Mater. Interfaces, 2016, 8, 6646–6655.

5.Shenna Chen, Qian Zhao, Lingyang Zhang, Linqian Wang, Yunlong Zeng, Haowen Huang*, Combined detection of breast cancer biomarkers based on plasmonic sensor of gold nanorods, Sensors and Actuators B: Chemical, 2015, 221, 1391-1397.

6.Lingyang Zhang, Shenna Chen, Qian Zhao, Haowen Huang*, Carbon dots as a fluorescent probe for label-free detection of physiological potassium level in human serum and red blood cells, Analytica Chimica Acta, 2015, 880, 130-135.

7.Shenna Chen, Qian Zhao, Lingyang Zhang, Xiaodong Xia, Haowen Huang*, Successive detection of glucose and bio-copper in human serum based on a multiplex biosensor of gold nanorods, Analytical Methods, 2015, 7, 1018-1025.

8.Qian Zhao, Shenna Chen, Lingyang Zhang, Haowen Huang*, Detection of Fe(III) and bio-copper in human serum based on fluorescent AuAg nanoclusters, Analytical Methods, 2015, 7, 296-300.

9.Qian Zhao, Shenna Chen, Lingyang Zhang, Haowen Huang* Fengping Liu, Xuanyong Liu*, Synthesis of biocompatible AuAgS/Ag2S nanoclusters and their applications in photocatalysis and mercury detection, Journal of Nanoparticle Research, 2014, 16, 2793.

10.Qian Zhao, Shenna Chen, Lingyang Zhang, Haowen Huang*, Yunlong Zeng, Fengping Liu, Multiplex sensor for detection of different metal ions based on on–off of fluorescent gold nanoclusters, Analytica Chimica Acta, 2014, 852, 236-243.

11.Qian Zhao, Shenna Chen, Haowen Huang*, Lingyang Zhang, Linqian Wang, Fengping Liu, Jian Chen, Yunlong Zeng, Paul K. Chu*. Colorimetric and ultra-sensitive fluorescence resonance energy transfer determination of H2O2 and glucose by multi-functional Au nanoclusters, Analyst, 2014, 139, 1498-1503.

12.Shenna Chen, Qian Zhao, Fang Liu, Haowen Huang*, Linqian Wang, Shoujun Yi, Yunlong Zeng, and Yi Chen*. Ultrasensitive determination of copper in complex biological media based on modulation of plasmonic properties of gold nanorods, Analytical Chemistry, 2013, 85, 9142–9147.

13.Haowen Huang*, Shenna Chen, Fang Liu, Qian Zhao, Bo Liao, Shoujun Yi, Yunlong Zeng, Multiplex plasmonic sensor for detection of different metal ions based on single type of gold nanorod, Analytical Chemistry, 2013, 85, 2312-2319.

14.Haowen Huang*, Fang Liu, Shenna Chen, Qian Zhao, Bo Liao, Yunfei Long, Yunlong Zeng, Xiaodong Xia, Enhanced fluorescence of chitosan based on size change of micelles and application to directly selective detecting Fe3+ in human serum, Biosensors and Bioelectronics, 2013, 42, 539-544. Haowen Huang*, Chunhui Li, Caiting Qu, Shaowen Huang, Fang Liu, Yunlong Zeng, Sensitive detection of DNA based on the optical properties of core–shell gold nanorods, Journal of Nanoparticle Research, 2012, 14, 754.

15.Haowen Huang*, Fang Liu, Shaowen Huang, Shishan Yuan, Bo Liao, Shoujun Yi, Yunlong Zeng, Paul K. Chu*, Sensitive and simultaneous detection of different disease markers using multiplexed gold nanorods, Analytica Chimica Acta, 2012, 755, 108-114.

16.Haowen Huang*, Caiting Qu, Xuanyong Liu, Shaowen Huang, Zhongjian Xu, Yingjie Zhu, Paul K. Chu*, Amplification of localized surface plasmon resonance signals by a gold nanorod assembly and ultra-sensitive detection of mercury, Chemical Communications, 2011, 47, 6897-6899.

17.Haowen Huang*, Shaowen Huang, Shishan Yuan, Caiting Qu, Yi Chen, Zhongjian Xu, Bo Liao, Yunlong Zeng, Paul K. Chu*, High-sensitivity biosensors fabricated by tailoring the localized surface plasmon resonance property of core–shell gold nanorods, Analytica Chimica Acta, 2011, 683, 242-247.

18.Haowen Huang*,Xuanyong Liu, Bo Liao, Paul K. Chu, A localized surface plasmon resonance biosensor based on integrated controllable Au2S/AuAgS-coated gold nanorods composite, Plasmonics, 2011, 6, 1-9.

19.Haowen Huang*, Caiting Qu, Xuangyong Liu, Shaowen Huang, Zhongjian Xu, Bo Liao, Yunlong Zeng, Paul. Chu*, Preparation of controllable core-shell gold nanoparticles and its application in detection of silver ions, ACS Applied Materials & Interfaces, 2011, 3, 183-190.

20.Haowen Huang*, Xuanyong Liu, Tao Hu, Paul K. Chu*, Ultra-sensitive detection of cysteine by gold nanorod assembly, Biosensor and Bioelectronics, 2010, 25, 2078-2083.

专利成果

[1]黄昊文,贺超才,曾云龙,夏晓东,连续可调控纵横比的金纳米棒制备方法,发明专利,ZL200710034358.6。

[2]黄昊文,贺超才,曾云龙,夏晓东,于贤勇,一种提高金纳米棒的纯度的方法,发明专利,ZL200710034760.4。

[3]黄昊文,贺超才,曾云龙,夏晓东,于贤勇,一种可调等离子体波的金纳米棒的制备方法,发明专利,ZL200710035251.3。

[4]黄昊文, 屈彩婷, 许中坚,易守军,一种制备核壳型金纳米粒子及用于检测银离子浓度的方法,发明专利,ZL 201010289193.9。

[5]黄昊文, 屈彩婷, 许中坚,易守军,廖博,一种基于金纳米棒自组装快速检测汞的方法,发明专利, ZL201110099983.5。

[6]黄昊文,陈甚娜,刘芳,赵倩,基于局域表面等离子体性质检测多种金属离子方法及其应用,发明专利,ZL201210554832.9。

[7]黄昊文,赵倩,陈甚娜,张凌阳,制备复合硫化银金/硫化银纳米簇的方法及其应用,发明专利,201310675248.3。

[8]黄昊文,张凌阳,赵倩,陈甚娜,微波辅助法制备碳点及用于检测钾离子浓度的方法及应用,发明专利,ZL201410430792.6。

[9]黄昊文,赵倩,陈甚娜,张凌阳,周媛,刘兰芳,一种基于金纳米簇模拟酶试剂盒及其制备方法及应用,发明专利号,ZL201510037912.0。

[10]黄昊文,周媛,赵倩,刘兰芳,张凌阳,一种基于乙二胺四乙酸模拟酶试剂盒的制备方法及其应用,发明专利号:ZL201510545849.1。

[11]黄昊文,张凌阳,刘兰芳,周媛,一种具有催化性能的碳点制备及基于此碳点试剂盒的应用,发明专利号,ZL201510545769.6。

奖励/荣誉

获湖南省2015年度自然科学二等奖(排名第一)。